![]() pulmonary veno-occlusive disease (PVOD).a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia.retinitis pigmentosa (an inherited condition of the eye).kidney disease (or if you are on dialysis).heart problems (chest pain, a heart rhythm disorder, heart failure).Some tadalafil can remain in your bloodstream for 2 or more days after each dose you take (longer if you have liver or kidney disease). Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Nitrates are also found in some recreational drugs such as amyl nitrate, butyl nitrate or nitrite ("poppers"). This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).ĭo not take tadalafil if you are also using a nitrate drug for chest pain or heart problems.You should not take tadalafil if you are allergic to it, or:
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